第41回KIT ライフサイエンスセミナーを開催しました。12/7（水）12:10。２号館4階 応用生物学系セミナー室（441室） 講演者：You Zhengying先生（浙江理工大学生命医科学部 准教授）
要旨：Spider dragline silk is a remarkable material that shows excellent mechanical properties, diverse applications, biocompatibility and biodegradability. Transgenic silkworm technology was used to obtain different types of chimeric silkworm/spider (termed composite) silk fiber including different lengths of recombinant Major ampullate Spidroin1/2 (reMaSp1/2) from the black widow spider, Latrodectus hesperus. We aimed to explore the relationship between the overall mechanical properties of composite silk fiber and the reMaSp1/2 chain length. The results indicated that there were significant linear relationships between the mechanical properties and the re-MaSp1 chain length, and the nature of various repetitive motifs in the primary structure played an important role in imparting excellent mechanical properties. We proposed the hypothesis that a single type of repetitive motif and sufficiently long chain were determined to be indispensable factors for the excellent mechanical properties of the silk fiber.